The Orwell Bridge near Ipswich is closed as Storm Isha hits the county with high winds.
National Highways closed the bridge at midday and it is due to remain shut until midday on Monday.
The Met Office has issued a yellow weather warning for strong winds up to 70mph and has warned some buildings could suffer damage, with injuries and danger to life from possible flying debris.
The decision to close the bridge at 12pm has been taken to allow road users to plan alternative routes and for National Highways to safely install the closure and diversions ahead of the predicted high winds.
READ MORE: Delays building in Ipswich after Storm Isha closes Orwell Bridge
The eastbound diversion will take traffic from the A14 at junction 55 Copdock Mill onto the A1214 through Ipswich before taking the second exit at Woodbridge Road roundabout onto the A1189 to Felixstowe Road.
This continues onto the A1156 before re-joining the eastbound A14 and junction 58 for Levington.
The westbound diversion will take the same route in reverse.
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Martin Fellows, National Highways regional director for the East, said: "We understand the inconvenience the closure of the Orwell Bridge causes across the region, but our priority will always be public safety.
"The high winds we are expecting mean it would be unsafe to try and operate the bridge under those conditions.
"Throughout the closure, we will continue to work with the Met Office and as soon as we are confident the bridge can be safely reopened, we will do so."
Road users are being advised to plan their journeys and allow additional time to travel.
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